Who should take IXIARO®?

IXIARO® is a vaccine to help prevent Japanese Encephalitis (JE). IXIARO® is indicated for active immunization against Japanese Encephalitis for persons 2 months of age and older.
As with any other vaccine, vaccination with IXIARO® may not result in protection in all cases. IXIARO® will not protect against encephalitis caused by other micro-organisms.

Who should not take IXIARO®?

Individuals with the following conditions should discuss vaccination with their physician, who will be able to advise on safe vaccination or alternative preventative measures to avoid infection with JEV:

  • Pregnant or breast-feeding women
  • Persons with bleeding disorder, or abnormal bruising
  • Persons with fever (temperature above 37.8°C)
  • Immunosuppressed persons or individuals on cancer treatment

Can IXIARO® cause any side effects?

The side effects of IXIARO® are usually mild.

The most commonly reported side effects in adults include headache, muscle pain, injection site pain/tenderness and tiredness.
The most commonly reported side effects in children and adolescents include fever, diarrhea, influenza-like illness, irritability and injection site reactions (pain, tenderness, redness).

Can I vaccinate my children with IXIARO®?

Yes. IXIARO® is indicated for active immunization against Japanese Encephalitis for persons 2 months of age and older.

Is IXIARO® covered by my insurance?

You may be covered for the IXIARO® vaccine with your private insurance.

Contact your insurance provider and give the IXIARO® drug identification number: 02333279.

When is IXIARO® recommended?

Vaccination should be considered for travellers to JE endemic/epidemic areas during the risk season and who are planning extensive outdoor activities (e.g., camping, trekking, biking) in rural areas, especially during evening or night.

How long before travelling do I need to take IXIARO®?

Primary immunization should be completed at least 1 week prior to potential exposure to JEV.

First dose must be taken at least 35 days before departure and second dose must be taken 7 days before departure as protection starts 7 days after the second dose.

A rapid immunization schedule may be used for people aged 18-65 years. In the rapid schedule, the first dose should be taken at least 14 days before departure and the second dose 7 days later.

Where can I get vaccinated?

Vaccines411.ca is a useful website that can help you find a location near you that offers IXIARO®.

What is Japanese Encephalitis (JE)?

Japanese Encephalitis is a serious disease found throughout Asia. It is transmitted by infected mosquitoes.

What are the symptoms of Japanese Encephalitis?

Patients developing overt illness usually experience flu-like symptoms such as high fever, nausea and vomiting, which may progress to seizures or coma.

While some patients experience a full recovery, JE can be fatal in 3 in 10 patients. 50% of patients who survive are left with permanent, long-term disabilities (e.g., paralysis, inability to talk).

How else can I protect myself against Japanese Encephalitis?

All travellers to Japanese Encephalitis endemic areas should take precautions to avoid mosquito bites. Prevention strategies include use of insect repellent, wearing proper clothing and reducing exposure to mosquitos during peak biting hours.

Does Japanese Encephalitis only occur in Japan?

No, JE is found in more 24 different countries across Asia and Southeast Asia, as well as parts of the western Pacific.

How many people are affected by Japanese Encephalitis?

Over 70,000 clinical cases are reported worldwide each year, although the figure could be much higher due to inadequate surveillance in many Asian countries where the virus is endemic.

Who is most at risk to develop Japanese Encephalitis?

It is not possible to predict who will develop the disease – the majority of infections in humans are asymptomatic; clinical disease develops in one in every 50 to 1,000 individuals infected.

Certain travellers, e.g., long-term travellers (>30 days), travellers who make multiple trips to endemic areas, persons staying for extended periods in rural areas and persons visiting an area suffering a JE outbreak, are likely at relatively higher risk for JE.

Is Japanese Encephalitis vaccine-preventable?

Yes. IXIARO® is a vaccine that helps prevent Japanese Encephalitis (JE).

Am I at risk for Japanese Encephalitis if I only stay in cities?

Although the risk of infection with JE virus may be lower in cities, cases of JE have been reported in urban and peri-urban regions.

Should I worry about Japanese Encephalitis if I’m only staying in Asia for less than 1 month?

Data show that more than one-third of travellers who developed JE were short-term travellers to Asia (less than 1 month).

Is Japanese Encephalitis fatal?

Up to 30% who develop JE die, and up to 50% of JE survivors suffer long-term neurologic, cognitive, and psychiatric impairment.

Is there treatment for Japanese Encephalitis?

No, there is no specific treatment for JE. Prevention is the best protection.

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